Professor of Radiology, Psychiatry & Biomedical Engineering
Director, Magnetic Resonance Spectroscopy
Email: AThomas@mednet.ucla.edu
Professional Training & Experience
To Date
Professor of Radiology, Psychiatry & Biomedical Engineering David Geffen School of Medicine at UCLA, Los Angeles CA
Director, MR Spectroscopy UCLA Radiological Sciences MR Physicist Consultant Harbor-UCLA Radiology Imaging Center
2000-2006
Associate Professor of Radiology UCLA Radiological Sciences
2000-2001
MR Consultant BF Research Institute GE 3T MRI Facility, Osaka, Japan
1993-2000
Assistant Professor of Radiology & Psychiatry UCLA Medical School, Los Angeles CA
1990-1993
Director, Clinical MR Spectroscopy Research University of Wisconsin, Madison WI Assistant Scientist of Radiology & Medical Physics University of Wisconsin, Madison WI
1990-1990
Postdoctoral Fellowship: Radiology & Medical Physics University of Wisconsin, Madison, WI
1987-1990
Visiting Assistant Research Spectroscopist Magnetic Resonance Unit Departments of Medicine V.A. Medical Center UCSF, San Francisco CA
Visiting Scientist: Physics Indian Institute of Science Bangalore, India
1984-1985
Postdoctoral Fellowship: Chemistry Purdue University, West Lafayette IN
1984
Doctor of Philosophy: in Nuclear Magnetic Resonance Spectroscopy Indian Institute of Science Bangalore, India
1978
Master of Science: in Physicis American College Madurai University Madurai, India
Research Interests
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Physics of MR imaging and spectroscopy
•
developments of new MR spectroscopic imaging (MRSI) techniques
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Evaluation of MRSI techniques in healthy tissues and in different pathologies
Current Research Projects
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Development of Multi-dimensional MR Spectroscopic Techniques and Evaluation in Different Diseases To implement 2-, 3- and 4-dimensional MRS techniques, and to evaluate them in human tissues
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Two-Dimensional MR Spectroscopic Characterization of HE To correlate the metabolite ratios using the 2D L-COSY sequence on a 1.5T MRI scanner with neuronpsychological test battery, and MRI of basal ganglia.
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Biochemical and Anatomical Correlates of Human Breast Cancer In Vivo To correlate the anatomical changes with that of the biochemicals (metabolites and lipids) in breast cancer and healthy women.
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A Novel Assay of Citrate, Choline, and Spermine in Prostate Cancer In Vivo To detect the biochemical changes in malignant and benign prostate cancer compared to healthy men.
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Neurobiological & Behavioral Substrates of Mood Disorders To record the anatomical and biochemical changes in geriatric depression.
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MR & Neuroendocrine Analysis of Bipolar Disorder and Alcohol Abuse Comorbidity To record the metabolite levels in bipolar & healthy controls
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Implementation and Evaluation of Cardiac MRSI in Humans To implement and evaluate cardiac proton MRS
